Y (MABp1) targeting IL-1 for the treatment of psoriasis. The role of IL-1 in cardiovascular diseases is not restricted to its proinflammatory function following myocardial infarction. Indeed, mounting evidence now suggests an important role for IL-1 in the development of atherosclerosis.167,168 This might come as a surprise because IL-1 has long been predicted to be the most important IL-1 cytokin